TRANSFORMING GROWTH FACTOR-β SIGNALING MODIFIES THE HEMATOPOIETIC ACUTE INFLAMMATORY RESPONSE TO DRIVE BONE MARROW FAILURE

Transforming growth factor-β signaling modifies the hematopoietic acute inflammatory response to drive bone marrow failure

Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells.They can be acquired during bone marrow stress or innate and are associated with driver genetic mutations.Patients with a bone marrow failure syndrome are at higher risk of developing secondary neoplasms, including myelod

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The JWST Resolved Stellar Populations Early Release Science Program. VIII. The Spatially Resolved Star Formation History of WLM

Radial stellar population gradients within dwarf galaxies provide a promising avenue for disentangling the drivers of galaxy evolution, including environment.Within the Local Volume, radial stellar age gradient slopes correlate with interaction history, contrary to model predictions, so dwarfs that are isolated provide a critical control sample.We

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